Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Headache
ADR ID BADD_A01965
ADR Hierarchy
17      Nervous system disorders
17.14      Headaches
17.14.01      Headaches NEC
17.14.01.001      Headache
Description A disorder characterized by a sensation of marked discomfort in various parts of the head, not confined to the area of distribution of any nerve. [CTCAE] The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS. [MeSH]
MedDRA Code 10019211
MeSH ID D006261; D006261; D006261; D006261; D020773; D006261; D051270
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Cephalalgia | Cephalalgia or cephalgia | Cephalgia | Forehead headache | Head pain | Head throbbing | Headache | Headache (except migraine) aggravated | Headache discomfort | Headache dull | Headache fullness | Headache NOS | Headache NOS aggravated | Headache occurring | Headache temporal | Headache transient | Hemicephalgia | Hemicrania | Nocturnal headache | Pain head | Pounding in head | Temporal headache | Headache aggravated | Frontal headache | Occipital headache | Parietal headache | Headache unilateral | Drug-induced headache | Frequent headaches | Chronic headaches | Headache (excl migraine) aggravated | Throbbing headache | Intermittent headache | Retroauricular pain | Headache recurrent | Hemicephalalgia | Ice pick headache | Headaches | Head Pain | Head Pains | Pain, Head | Pains, Head | Cephalodynia | Cephalodynias | Cranial Pain | Cranial Pains | Pain, Cranial | Pains, Cranial | Cephalalgias | Cephalgias | Generalized Headache | Generalized Headaches | Headache, Generalized | Headaches, Generalized | Ocular Headache | Headache, Ocular | Headaches, Ocular | Ocular Headaches | Orthostatic Headache | Headache, Orthostatic | Headaches, Orthostatic | Orthostatic Headaches | Vertex Headache | Headache, Vertex | Headaches, Vertex | Vertex Headaches | Retro-Ocular Headache | Headache, Retro-Ocular | Headaches, Retro-Ocular | Retro Ocular Headache | Retro-Ocular Headaches | Sharp Headache | Headache, Sharp | Headaches, Sharp | Sharp Headaches | Throbbing Headache | Headache, Throbbing | Headaches, Throbbing | Throbbing Headaches | Unilateral Headache | Headache, Unilateral | Headaches, Unilateral | Unilateral Headaches | Bilateral Headache | Bilateral Headaches | Headache, Bilateral | Headaches, Bilateral | Periorbital Headache | Headache, Periorbital | Headaches, Periorbital | Periorbital Headaches
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Cytochrome P450 2D6P10635T57392
Cytochrome P450 3A4P08684T37848
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00170Articaine hydrochloride--
BADD_D00172Asenapine--
BADD_D00173Asenapine maleate--
BADD_D00174Asfotase alfa--
BADD_D00176Atazanavir--
BADD_D00177Atazanavir sulfate--
BADD_D00178Atenolol0.001811%
BADD_D00180Atomoxetine0.008927%
BADD_D00181Atomoxetine hydrochloride--
BADD_D00182Atorvastatin calcium--
BADD_D00185Atosiban--
BADD_D00186Atovaquone--
BADD_D00189Atropine0.001030%
BADD_D00190Atropine sulfate--
BADD_D00192Avanafil--
BADD_D00193Axitinib--
BADD_D00194Azacitidine--
BADD_D00195Azathioprine--
BADD_D00198Azelastine--
BADD_D00199Azelastine hydrochloride--
BADD_D00202Azilsartan medoxomil0.000229%
BADD_D00203Azithromycin--
BADD_D00204Azithromycin dihydrate--
BADD_D00205Azithromycin monohydrate--
BADD_D00206Aztreonam--
BADD_D00207Bacillus calmette-guerin--
BADD_D00209Baclofen--
BADD_D00210Balsalazide--
BADD_D00211Balsalazide disodium--
BADD_D00214Basiliximab--
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